Prof. Dr. med. Matthias Schwab
Professor and Chair of Clinical Pharmacology,
Head of the Dr. Margarete Fischer-Bosch-Institute
of Clinical Pharmacology, Stuttgart
and
Department of Clinical Pharmacology,
Institute of Experimental and Clinical Pharmacology and Toxicology,
University Hospital, Tübingen
Dr. Margarete Fischer-Bosch-Institut für Klinische Pharmakologie
Auerbachstrasse 112
70376 Stuttgart
Phone: +49 (0) 711 - 8101 3700
Fax: +49 (0) 711 - 859 295
e-mail: matthias.schwab(AT)ikp-stuttgart.de
Professional Activities
- Civilian service as house officer and later as senior house officer at the Children’s Hospital, Nuernberg, Germany (Prof. Dr. H.Gröbe) (1990 - 1993)
- Senior house officer at the University Hospital of Children and Adolescents, Friedrich-Alexander University of Erlangen-Nuernberg, Erlangen, Germany (Prof. Dr. C. Stehr) (1993 - 1995)
- Fellow in clinical pharmacology at the Dr Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany (Prof. Dr. M. Eichelbaum) (1995 - 2001)
- Coordinator of the research focus „Pharmacogenetics“ at the Dr Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany (Prof. Dr. M. Eichelbaum) (2000 – 2005)
- Senior physician and Head of the Research Unit for Clinical Trials and Drug Information Centre at the Dr Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany (Prof. Dr. M. Eichelbaum) (2001 - 2005)
- Visiting Professor, St. Jude Children’s Research Hospital, Department of Pharmaceutical Sciences, Memphis, Tennessee, USA (Prof. W.E. Evans; Focus on “Pharmacogenomics”) (2005 - 2006)
- Decline of professorship for Clinical Pharmacology, Medical University Innsbruck, Austria (2006)
- Professor and Chair of Clinical Pharmacology (W3/C4), Eberhard Karl University Tuebingen, Germany and Head of the Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, and the Department of Clinical Pharmacology, University Hospital, Tuebingen (1/2007 – present)
Education
- Study of medicine, Friedrich-Alexander University of Erlangen-Nürnberg (1983 -1990)
- Doctor`s degree of medicine, Institute of Toxicology and Pharmacology, University Erlangen Nürnberg (Prof. Dr. R. Böcker und Prof. Dr. C. Estler). Title of thesis: "Impact of subchronic treatment of mice with nifedipin on hepatic cytochrom P-450 isoenzyme activities in comparison to enzyme activities in different species." (1991)
- State Licence as medical doctor (1992)
- Board certification: Paediatrics and Adolescent Medicine (1996)
- Special qualification as emergency physician for newborns (acc to DÖGNPI), education for paediatric nephrology, additional certification in: Paediatric ultrasonography of the thyroid gland of head and neck, of the gastrointestinal tract and of female genitals, certification in addiction medicine in children and adolescents, certification in radiological diagnostics for thoracic organs, certification in basic psychosomatic medicine
- Board certification: Clinical Pharmacology (2000)
- Qualification as university lecturer (Habilitation) for „Clinical Pharmacology and Paediatric Pharmacology“ at the Eberhard-Karls University Tuebingen (Prof. Dr. Osswald) Title: "Relevance of genetic polymorphisms of P-glycoprotein and thiopurine S-methyltransferase for development and therapy of inflammatory bowel disease" (2003)
Honours / Memberships
- Scholarship according to the "Bayerischen Begabtenförderungsgesetz" (1983 - 1990)
- Full member of the "Committee of Drug Safety" of the German Society of Child and Adolescent Medicine (Chair: Prof. Dr. Seyberth, Marburg) (1998 - present)
- Member of the Research Committee at the Robert-Bosch Hospital, Stuttgart (1999 - 2005)
- Full Member of the Expert Group "Drugs for Children and Adolescents" at the German Federal Institute of Drugs and Medicinal products (BfArM) (2002 - 2004)
- Member of the Expert Group "HEXAL-Iinitiative drugs for children" (2004 - present)
- Member of the ethical committee of the Landesärztekammer Baden-Württemberg (2004 - present)
- Friedrich Hartmut-Dost Award (2004)
- extraordinary member of the CPMP Pediatric Expert Group (PEG) of the EMEA in London (authorized by German Society of Child and Adolescent Medicine) (2001 - 2004)
- Galenus von Pergamon Award (2005)
- Full member (2006) and Vice Chair (2008) of the Expert Group "Drugs for Children and Adolescents" at the German Federal Institute of Drugs and Medicinal products (BfArM) (2006 – 2009)
- Chairman of the board of scientist at the Robert-Bosch Hospital/IKP, Stuttgart (2007 - present)
- Member of the „Drug Commission of the German Medical Association (AkdÄ) (2007 - present)
- Member of IUPHAR Division of Clinical Pharmacology - Sub-Committee Pharmacogenetics (2008)
- Re-Call: Full member and Vice Chair of the Expert Group "Drugs for Children and Adolescents" according to AMG at the German Federal Institute of Drugs and Medicinal products (BfArM) (2009)
- Member of the medical executive board of the Robert Bosch Hospital, Stuttgart (2009)
- Member of the Chair of the Comprehensive Cancer Center (CCC) of the University Hospital, Tuebingen (2009)
- Full member of the American Society for Clinical Pharmacology and Therapeutics (ASCPT) (2010)
Editorial Boards / Editor
- Section Editor "Personalized Therapy" of genome Medicine
- Editor of "Pharmacogenet Genomics" (from 2010)
- Clinical Chemistry
- Therapeutic Drug Monitoring
Publications: > 230
Talks: > 300
Main Research Interests
- Pharmacogenomics / Epigenetics of drug metabolizing enzymes, drug transporters and nuclear receptors
- Pharmacogenomics of anticancer and immunosuppressive drugs
- Drug Interaction
- Pediatric clinical pharmacology
- Novel methodologies in genomic research